Sjögren’s syndrome (SS), also known as Sicca syndrome, is a relatively common autoimmune disease, affecting around 0.5% of adults, which is about 500 000 people in the UK. Its prevalence increases with age and it is much more common in women, with a ratio of 9:1 to men. The disease usually starts between the ages 40 and 60 and is rarely seen in children and adolescents.
The condition can be subdivided into primary Sjögren’s syndrome (PSS), with no underlying disease, or secondary (SSS) when it is associated with other autoimmune conditions such as rheumatoid arthritis, systemic lupus erythematosus (SLE) or primary biliary cirrhosis (Carr et al. 2012).
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