Sepsis is not a new concept or word. It is found cited in ancient Greek manuscripts by both Homer and Hippocrates to mean ‘I rot’ and ‘decomposition of animal, or vegetable or organic matter in the presence of bacteria’ (Funk et al, 2009).Over the centuries, even with the advancement of medical knowledge and research, combined with the discoveries of antibiotic therapies, sepsis continued to be a condition that remained a mystery. Many patients would continue to die – even after the removal of the disease-causing agent (Angus & van der Poll, 2013).Further research has led to the discovery that sepsis is in fact the response of the host, rather than the germ itself (Cerra, 1985).
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