Local-anaesthetic-related nerve damage

Local anaesthetic is a drug that produces loss of sensation without loss of consciousness by reversibly blocking nerve conduction and thus preventing the transmission of pain to the brain. The action of local anaesthetics is limited to a small area (hence the term ‘local’ anaesthetic). They work quickly and are easily broken down, resulting in sensation being returned to normal shortly after administration. However, despite being somewhat of a wonder drug, the administration of local anaesthetic does not come without its complications. Unwanted effects of local anaesthetic can be due to either the administration technique, the anaesthetic agent, the vasoconstrictor (commonly adrenalin) or another additive of the local anaesthetic solution.