The strength of evidence to support the effectiveness of preventive and therapeutic procedures is graded as follows:
Systematic reviews – highest level
Randomised controlled trials (RCTs)
Observational/reported behaviour
Opinion/traditional reviews.
The Cochrane Oral Health Group, based in Manchester, collates evidence from randomised controlled trials of preventive and therapeutic measures and performs systematic reviews of these. The findings from systematic reviews provide the strongest evidence about how effective treatments are. This article provides a summary of the evidence which supports the advice that should be given to patients by dental professionals.
What is the strength of evidence to demonstrate that fluoride toothpastes are effective in reducing the prevalence, incidence and severity of dental caries?
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