Researchers have created a three-dimensional model of the oral mucosa that can be used in studies to test its response to a range of bacterial and other infections. The model, created by experts in dentistry and immunology at the university, is formed from a collagen hydrogel containing cell types commonly found in the human body.
In a series of tests, the researchers analysed the model’s response to a range of pathogens, including Candida albicans and Staphylococcus aureus.
The team found it behaved similarly to responses observed in other studies involving real patients, indicating it could be implemented for the wider study of oral infection.
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