Oral inflammation reduced by a fasting-mimicking diet

In a feasibility study carried out by King’s College London, a research team explored the potential benefits of incorporating a FMD together with the standard non-surgical periodontal therapy to treat patients with severe gum disease.

The study titled ‘The application of a Fasting-mimicking Diet in Periodontitis. A feasibility study’, was published in the Journal of Dentistry.

Unlike traditional fasting, which requires complete abstinence from food, a FMD is a carefully designed, low-calorie diet that provides essential nutrients while inducing a fasting-like state in the body. Existing evidence has revealed that this approach triggers cellular and metabolic responses similar to prolonged fasting, including reduced inflammation and enhanced tissue repair, but with greater adherence and reduced discomfort compared to complete fasting.