
Periodontal disease, often caused by the formation and accumulation of bacterial biofilm around the teeth, can lead to tooth loss if left unattended. According to researchers, the inflammatory effects of periodontal bacteria can go well beyond the mouth, leading to systemic effects.
Previous studies have revealed that the periodontal pathogen Aggregatibacter actinomycetemcomitans is closely related to the onset and worsening of rheumatoid arthritis (RA), a serious autoimmune disease that affects joints.
The latest research
In a study published in August 2024 in the International Journal of Oral Science, a research team from Tokyo Medical and Dental University (TMDU) explored this on a molecular through detailed mechanistic studies in an animal model.
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