Linnette Cruz, a 51-year-old mother-of-one, passed away two days ago.
She was a senior head nurse at the Brynteg dental practice in the Swansea area of Sketty, and was admitted to hospital last month after suffering with COVID-19 symptoms.
Friends and colleagues are devastated by her death.
Linnette was being treated at the intensive care unit at Morriston Hospital.
Karl Bishop, dental director for the Swansea Bay University Health Board, said: 'Linnette's death is deeply upsetting to her family, friends and colleagues and all our thoughts are with them.
'She was a highly committed and caring dental nurse, respected by her colleagues, patients and the communities in which she worked.
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