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Baby teeth link to ADHD and autism

1 min read Special care dentistry
​Researchers have identified elemental signatures in baby teeth that are unique to attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, and cases when both neurodevelopment conditions are present.

The findings suggests that the metabolic regulation of nutrients and toxins play a role in these diseases, according to a study published in Translational Psychiatry in September.

The researchers used baby teeth to reconstruct prenatal and early-life exposures to nutrients and toxic elements in neurotypical children and children with autism, ADHD, or ADHD and autism. They found that each condition has a unique metabolic signature, which shows a combination of dysregulation in metabolic pathways involving essential and toxic elements.

'Environmental epidemiologists typically study exposure to essential and toxic elements by examining how much of a given element a child was exposed to, but our work indicates that the way a child metabolizes environmental exposures is essential to healthy neurodevelopment,' said Paul Curtin, PhD, Assistant Professor of Environmental Medicine and Public Health at the Icahn School of Medicine at Mount Sinai.

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