The National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health, has awarded NYU College of Dentistry's Yi Ye, PhD, the cash boost as a five-year grant to study the role of Schwann cells, the most prevalent type of cell supporting neurons in the peripheral nervous system, in oral cancer progression and pain.
Oral cancer patients suffer from excruciating pain with their ability to speak, eat, and drink often severely impaired.
Cancer penetrates the nerve, a process termed perineural invasion, causing pain and making the cancer more difficult to treat. How oral cancer invades nerves and causes pain is poorly understood.
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