Cystic fibrosis (CF) is an inherited disease of the secretory glands and it is the most common serious autosomal recessive disorder in the Caucasian population, with a frequency of 1 in 2 500 live births in the UK (Rolim et al, 2010; Bimstein et al, 2011). The mutation is found in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene (Riordan et al, 1989).
The tissues affected by CF include sweat glands, intestine, pancreatic ducts, respiratory epithelia, submandibular glands, uterus and bile ducts. Lung disease is the main cause of morbidity and mortality in CF.
It has been reported that CF patients have abnormal dentitions with problems relating either to the disease itself or as a treatment consequence (Jagels and Sweeney, 1976; Kinirons, 1989; Kinirons, 1992; Narang et al, 2003).
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